CSF β2 Transferrin/Beta Trace Protein
ACCREDITATION STATUS:
UKAS accredited proficiency testing provider No. 7795
CLINICAL APPLICATION:
The diagnosis of cerebrospinal fluid (CSF) rhinorrhea or otorrhea (leakage of CSF into the nose or ear canal, usually as a result of head trauma, tumor, congenital malformation, or surgery) is often difficult to confirm. CSF B2 Transferrin testing is used to determine the presence or absence of CSF (in serum) in such cases. Beta 2 Transferrin is only found in CSF, ocular fluids and perilymph, therefore it can be used as a marker to determine the presence of CSF in various secretions (typically from the nose and ear)
PURPOSE OF PROGRAMME:
Immunochemistry EQA scheme
ANALYTES:
Analyte | Default Unit |
---|---|
CSF β2 Transferrin | Qualitative: Positive /Negative Quantitative: mg/L |
β Trace Protein | Qualitative: Positive /Negative Quantitative: mg/L |
MATERIAL PROVIDED: Normal and pathological human serum. Serum based or CSF samples
DISTRIBUTIONS PER YEAR: 6
SAMPLES PER DISTRIBUTION: 2
FREQUENCY OF DISTRIBUTION: Every two months as outlined in the Distribution Schedule
PROGRAMME OF ANALYSIS:
Data entry is via the web for the submission of results. Data analysis is commenced 21 days after sample dispatch. Late returns are accepted and will contribute to the laboratory's cumulative performance statistics
DATA ANALYSIS:
Qualitative responses are assessed by MI scoring in relation to the designated response
PERFORMANCE SCORING:
MI scoring
PERFORMANCE MONITORING:
Laboratory performance is assessed over a running analytical window of 6 Distributions (12 months). Pilot scoring has been introduced:
PERSISTENT POOR PERFORMANCE:
Defined as being in the Poor Performance category for two or more successive Distributions
Immunology, Immunochemistry & Allergy (IIA)
The External Quality Assessment Scheme for Immunology, Immunochemistry & Allergy (IIA) was founded in 1982 by Dr Anthony Milford Ward at Northern General Hospital, Sheffield. In 1982 the Service became known as the UK National External Quality Assessment Service for Immunology, Immunochemistry & Allergy. UK NEQAS IIA is part of the Sheffield Teaching Hospitals NHS Foundation Trust. For the most up-to-date scheme information (including any pilot schemes) please contact the centre directly.
Contact Details
- UK NEQAS Immunology, Immunochemistry & Allergy
- Sheffield Teaching Hospitals NHS Foundation Trust
- PO Box 894
- Sheffield
- S5 7YT
Immunology, Immunochemistry & Allergy (IIA)
- Telephone: +44 (0) 114 271 5715
- Email: ukneqas@immqas.org.uk
- Web: https://www.immqas.org.uk/