Prostate Specific Antigen (PSA)
ACCREDITATION STATUS:
UKAS accredited proficiency testing provider No. 7795
CLINICAL APPLICATION:
Diagnosis and management of prostate carcinoma
PURPOSE OF PROGRAMME:
Oncology EQA scheme
ANALYTES:
| Analyte | Default Unit |
|---|---|
| Complexed PSA together with the derived PSA indices. | |
| Free PSA | |
| Total PSA | µg/L (total, free and complexed PSA) in relation to the WHO International Standard |
Each analyte is available separately
MATERIAL PROVIDED: Liquid format. Normal and pathological human serum. Additional materials may be produced for specific recovery experiments by the addition of purified Free PSA and/or PSA-ACT complex to analyte free h
DISTRIBUTIONS PER YEAR: 2
SAMPLES PER DISTRIBUTION: 12
FREQUENCY OF DISTRIBUTION: Every month as outlined in the Distribution Schedule
PROGRAMME OF ANALYSIS:
Data entry is via the web for the submission of results. Data analysis is commenced 14 days after sample dispatch. Late returns are accepted and will contribute to the laboratory's cumulative performance statistics
DATA ANALYSIS:
All Laboratory Trimmed Mean (ALTM) with truncation at 2SD, SD, and CV%. Reports also show method specific statistics. Individual laboratory performance is expressed in terms of MRBIS, SDBIS, and MRVIS Chosen Coefficient of Variation for Prostate Specific Antigen is 7% Chosen Coefficient of Variation for Free Prostate Specific Antigen is 10% Chosen Coefficient of Variation for Complexed Prostate Specific Antigen is 10%
PERFORMANCE SCORING:
MRVIS
PERFORMANCE MONITORING:
Laboratory performance for Total PSA, Free PSA and Complexed PSA is classified in terms of the MRVIS over a running analytical window of 12 Distributions (12 months)
PERSISTENT POOR PERFORMANCE:
Defined as being in the Poor Performance category for two or more successive Distributions
Immunology, Immunochemistry & Allergy (IIA)
The External Quality Assessment Scheme for Immunology, Immunochemistry & Allergy (IIA) was founded in 1982 by Dr Anthony Milford Ward at Northern General Hospital, Sheffield. In 1982 the Service became known as the UK National External Quality Assessment Service for Immunology, Immunochemistry & Allergy. UK NEQAS IIA is part of the Sheffield Teaching Hospitals NHS Foundation Trust. For the most up-to-date scheme information (including any pilot schemes) please contact the centre directly.
Contact Details
- UK NEQAS Immunology, Immunochemistry & Allergy
- Sheffield Teaching Hospitals NHS Foundation Trust
- PO Box 894
- Sheffield
- S5 7YT
Immunology, Immunochemistry & Allergy (IIA)
- Telephone: +44 (0) 114 271 5715
- Email: ukneqas@immqas.org.uk
- Web: https://www.immqas.org.uk/